Collaboration and Research Arrangements - Summary of Changes in Contract Assets and Liabilities (Details) $ in Thousands	12 Months Ended
	Dec. 31, 2022 USD ($)
Disaggregation Of Revenue [Line Items]
Accounts receivable and contract assets, Balance at Beginning of Period	$ 2,979
Accounts receivable and contract assets, Additions	19,484
Accounts receivable and contract assets, Deductions	(20,769)
Accounts receivable and contract assets, Balance at End of Period	1,694
Contract liabilities, Balance at Beginning of Period	10,181
Contract liabilities, Additions	2,944
Contract liabilities, Deduction	(8,795)
Contract liabilities, Balance at End of Period	4,330
Incyte
Disaggregation Of Revenue [Line Items]
Contract liabilities, Balance at Beginning of Period	1,268
Contract liabilities, Deduction	(1,268)
Global Blood Therapeutics
Disaggregation Of Revenue [Line Items]
Contract liabilities, Balance at Beginning of Period	8,913
Contract liabilities, Additions	2,944
Contract liabilities, Deduction	(7,527)
Contract liabilities, Balance at End of Period	4,330
Billed receivables from collaboration partners
Disaggregation Of Revenue [Line Items]
Accounts receivable, Additions	10,315
Accounts receivable, Deduction	(10,315)
Unbilled receivables from collaboration partners
Disaggregation Of Revenue [Line Items]
Contract assets, Balance at Beginning of Period	2,979
Contract assets, Additions	9,169
Contract assets, Deduction	(10,454)
Contract assets, Balance at End of Period	$ 1,694