Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF CASH FLOWS

CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Operating activities
Net loss	$ (94,654)	$ (86,558)	$ (84,038)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	2,706	2,758	2,774
Amortization of right-of-use asset	261	260	261
Transaction costs allocated to warrants issued in connection with private placement	5,015
Stock-based compensation expense	11,410	10,354	10,939
Change in fair value of warrant liabilities	(43,221)	(16,682)	375
Net amortization of premiums and discounts on marketable securities	243	224	(49)
Amortization of debt-discount and accretion of deferred debt costs	692	706	287
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	(2,807)	(995)	309
Accounts receivable		7	19,993
Contract assets	1,285	(655)	(2,166)
Other long-term assets	(2,407)	(1,196)	(1,269)
Accounts payable	2,766	48	(1,057)
Accrued expenses	2,345	4,830	593
Deferred revenue	(5,851)	(11,905)	(6,292)
Proceeds for tenant improvement incentive from landlord			2,035
Operating lease asset and liabilities	(848)	(736)	(59)
Net cash used in operating activities	(123,065)	(99,540)	(57,364)
Investing activities
Purchases of property and equipment	(1,241)	(1,245)	(3,336)
Purchases of marketable securities		(51,408)
Maturities of marketable securities	68,426		50,000
Net cash (used in) provided by investing activities	67,185	(52,653)	46,664
Financing activities
Payments on financing lease obligations	(291)	(265)	(241)
Proceeds from issuance of common stock through employee benefit plans		157	1,076
Proceeds from the issuance of common stock through employee stock purchase plan	217	323	433
Proceeds from the issuance of common stock through exercise of option	1	200	1,100
Payment to creditor related to debt modification	(300)
Proceeds from issuance of common stock through at-the-market sales agreement, net of issuance costs			11,896
Proceeds from term loan, net of issuance costs			39,619
Cash and cash equivalents acquired in connection with merger,net of issuance costs paid	11,762
Proceeds from issuance of common stock and accompanying warrants and pre-funded warrants in private placement, net of issuance costs	119,761		90,377
Proceeds from issuance of common stock and warrants in public offerings, net of issuance costs		70,337
Cash paid in lieu of fractional shares due to the reverse stock split	81
Payment of issuance costs related to out of period offering	(24)	(41)	(207)
Net cash provided by financing activities	131,045	70,511	142,953
Net increase (decrease) in cash, cash equivalents and restricted cash	75,165	(81,682)	132,253
Cash and cash equivalents, Beginning of period	95,388	177,070	44,817
Cash and cash equivalents, End of period	170,553	95,388	177,070
Supplemental disclosure of cash flow information:
Cash paid for interest	3,408	3,191	1,505
Cash paid for tax			7
Non-cash investing and financing activities:
Property and equipment received but unpaid as of period end		26	6
Deferred debt financing costs incurred but unpaid as of period end		24	5
Offering costs incurred but unpaid as of period end	$ 10	$ 10	$ 298