| Schedule of selected quarterly financial information |
|
|
|
Three Months Ended
|
|
|
|
|
March 31, 2020
|
|
|
June 30, 2020
|
|
|
September 30, 2020
|
|
|
December 31, 2020
|
|
|
Revenue
|
|
$
|
2,379
|
|
|
$
|
3,188
|
|
|
$
|
3,828
|
|
|
|
5,698
|
|
|
Operating expenses:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Research and development
|
|
|
14,569
|
|
|
|
14,796
|
|
|
|
17,674
|
|
|
|
29,026
|
|
|
General and administrative
|
|
|
5,149
|
|
|
|
5,133
|
|
|
|
5,151
|
|
|
|
5,892
|
|
|
Total operating expenses
|
|
|
19,718
|
|
|
|
19,929
|
|
|
|
22,825
|
|
|
|
34,918
|
|
|
Loss from operations
|
|
|
(17,339
|
)
|
|
|
(16,741
|
)
|
|
|
(18,997
|
)
|
|
|
(29,220
|
)
|
|
Interest income
|
|
|
384
|
|
|
|
32
|
|
|
|
4
|
|
|
|
6
|
|
|
Interest expense
|
|
|
(271
|
)
|
|
|
(487
|
)
|
|
|
(493
|
)
|
|
|
(541
|
)
|
|
Change in fair value of warrant liability
|
|
|
—
|
|
|
|
—
|
|
|
|
—
|
|
|
|
(375
|
)
|
|
Net loss applicable to common stockholders
|
|
$
|
(17,226
|
)
|
|
$
|
(17,196
|
)
|
|
$
|
(19,486
|
)
|
|
|
(30,130
|
)
|
|
Net loss per share applicable to common stockholders - basic and diluted
|
|
$
|
(0.39
|
)
|
|
$
|
(0.38
|
)
|
|
$
|
(0.43
|
)
|
|
|
(0.62
|
)
|
|
Weighted-average number of common shares used in net loss per share applicable to common stockholders - basic and diluted
|
|
|
43,923,999
|
|
|
|
45,699,277
|
|
|
|
45,781,638
|
|
|
|
48,774,598
|
|
|
|
|
Three Months Ended
|
|
|
|
|
March 31, 2019
|
|
|
June 30, 2019
|
|
|
September 30, 2019
|
|
|
December 31, 2019
|
|
|
Revenue
|
|
$
|
454
|
|
|
$
|
462
|
|
|
$
|
558
|
|
|
$
|
508
|
|
|
Operating expenses:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Research and development
|
|
|
12,562
|
|
|
|
15,475
|
|
|
|
15,931
|
|
|
|
14,277
|
|
|
General and administrative
|
|
|
4,865
|
|
|
|
5,195
|
|
|
|
5,016
|
|
|
|
6,402
|
|
|
Total operating expenses
|
|
|
17,427
|
|
|
|
20,670
|
|
|
|
20,947
|
|
|
|
20,679
|
|
|
Loss from operations
|
|
|
(16,973
|
)
|
|
|
(20,208
|
)
|
|
|
(20,389
|
)
|
|
|
(20,171
|
)
|
|
Interest income
|
|
|
520
|
|
|
|
776
|
|
|
|
617
|
|
|
|
462
|
|
|
Interest expense
|
|
|
(8
|
)
|
|
|
(23
|
)
|
|
|
(21
|
)
|
|
|
(20
|
)
|
|
Net loss applicable to common stockholders
|
|
$
|
(16,461
|
)
|
|
$
|
(19,455
|
)
|
|
$
|
(19,793
|
)
|
|
$
|
(19,729
|
)
|
|
Net loss per share applicable to common stockholders - basic and diluted
|
|
$
|
(0.49
|
)
|
|
$
|
(0.47
|
)
|
|
$
|
(0.47
|
)
|
|
$
|
(0.46
|
)
|
|
Weighted-average number of common shares used in net loss per share applicable to common stockholders - basic and diluted
|
|
|
33,766,333
|
|
|
|
41,673,275
|
|
|
|
42,439,338
|
|
|
|
42,885,208
|
|
|