Annual report pursuant to Section 13 and 15(d)

CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY

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CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS' EQUITY - USD ($)
$ in Thousands
Total
Warrants Related To debt arrangement
Incyte
At The Market
Follow On Offering
Follow On Offering
Common Stock and Warrants
Follow On Offering
Preferred Stock and Warrants
Private Placement
Private Placement
Pre-Funded Warrant
Common Stock
Common Stock
Incyte
Common Stock
At The Market
Common Stock
Follow On Offering
Common Stock
Follow On Offering
Common Stock and Warrants
Common Stock
Private Placement
Common Stock
Private Placement
Pre-Funded Warrant
Series A Convertible Preferred Stock
Series A Convertible Preferred Stock
Follow On Offering
Preferred Stock and Warrants
Additional Paid-In Capital
Additional Paid-In Capital
Warrants Related To debt arrangement
Additional Paid-In Capital
Incyte
Additional Paid-In Capital
At The Market
Additional Paid-In Capital
Follow On Offering
Additional Paid-In Capital
Follow On Offering
Common Stock and Warrants
Additional Paid-In Capital
Follow On Offering
Preferred Stock and Warrants
Additional Paid-In Capital
Private Placement
Additional Paid-In Capital
Private Placement
Pre-Funded Warrant
Accumulated Other Comprehensive (Loss) Gain
Accumulated Deficit
Balance at Dec. 31, 2017 $ 65,324                 $ 26                 $ 220,606                 $ (42) $ (155,266)
Balance (in shares) at Dec. 31, 2017                   26,423,375                                      
Exercise of stock options 626                                   626                    
Exercise of stock options, Shares                   214,533                                      
Issuance of common stock / preferred stock, warrants, net of issuance costs     $ 7,648 $ 16,538 $ 42,700     $ 1,380     $ 1 $ 1 $ 6               $ 7,647 $ 16,537 $ 42,694     $ 1,380      
Issuance of common stock / preferred stock, warrants, net of issuance costs (in shares)                     793,021 1,373,677 4,816,753   144,505                            
Stock-based compensation expense 6,610                                   6,610                    
Other comprehensive gain (loss) 39                                                     39  
Net loss (62,279)                                                       (62,279)
Balance at Dec. 31, 2018 78,586                 $ 34                 296,100                 (3) (217,545)
Balance (in shares) at Dec. 31, 2018                   33,765,864                                      
Exercise of stock options 211                                   211                    
Exercise of stock options, Shares                   60,181                                      
Issuance of common stock / preferred stock, warrants, net of issuance costs       799   $ 60,359 $ 4,638             $ 9               799   $ 60,350 $ 4,638        
Issuance of common stock / preferred stock, warrants, net of issuance costs (in shares)                       180,787   8,667,333       666                      
Conversion of preferred stock, Shares                   666,000             (666)                        
Issuance of shares under Employee Stock Purchase Plan 161                                   161                    
Issuance of shares under Employee Stock Purchase Plan, Shares                   27,386                                      
Exercise of warrants 2                                   2                    
Exercise of warrants, Shares                   250                                      
Stock-based compensation expense 9,839                                   9,839                    
Other comprehensive gain (loss) 27                                                     27  
Net loss (75,438)                                                       (75,438)
Balance at Dec. 31, 2019 $ 79,184                 $ 43                 372,100                 24 (292,983)
Balance (in shares) at Dec. 31, 2019 43,367,801                 43,367,801                                      
Balance (in shares) at Dec. 31, 2019 0                                                        
Exercise of stock options $ 1,076                                   1,076                    
Exercise of stock options, Shares 170,723                 170,723                                      
Vesting of restricted stock units                   109,362                                      
Issuance of common stock / preferred stock, warrants, net of issuance costs   $ 302   $ 11,919         $ 70,753     $ 2       $ 11       $ 302   $ 11,917         $ 70,742    
Issuance of common stock / preferred stock, warrants, net of issuance costs (in shares)                       2,201,810       10,312,500                          
Issuance of shares under Employee Stock Purchase Plan $ 433                                   433                    
Issuance of shares under Employee Stock Purchase Plan, Shares                   59,550                                      
Exercise of warrants 9                                   9                    
Exercise of warrants, Shares                   1,000                                      
Stock-based compensation expense 10,939                                   10,939                    
Other comprehensive gain (loss) (24)                                                     $ (24)  
Net loss (84,038)                                                       (84,038)
Balance at Dec. 31, 2020 $ 90,553                 $ 56                 $ 467,518                   $ (377,021)
Balance (in shares) at Dec. 31, 2020 56,222,746                 56,222,746                                      
Balance (in shares) at Dec. 31, 2020 0