Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies - License Agreement - Additional Information (Details)

v3.22.0.1
Commitments and Contingencies - License Agreement - Additional Information (Details) - TMRC - USD ($)
1 Months Ended 12 Months Ended
Sep. 30, 2021
May 31, 2021
May 31, 2016
Sep. 30, 2015
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2016
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]                
Up-front license fee       $ 1,000,000.0        
Payment of up-front license fee     $ 500,000 500,000        
Payments per indication due upon the successful achievement of clinical and regulatory milestones       $ 13,000,000.0        
Payments made upon achievement of development milestone $ 1,000,000.0 $ 2,000,000.0           $ 1,000,000.0
Fees incurred under supply management agreement         $ 600,000 $ 900,000    
Payments made under the supply management agreement             $ 0