Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies - License Agreements (Details)

v3.10.0.1
Commitments and Contingencies - License Agreements (Details) - TMRC - USD ($)
$ in Millions
1 Months Ended 12 Months Ended
Sep. 30, 2016
May 31, 2016
Sep. 30, 2015
Dec. 31, 2018
Dec. 31, 2017
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]          
Up-front license fee     $ 1.0    
Payment of up-front license fee   $ 0.5 0.5    
Payments per indication due upon the successful achievement of clinical and regulatory milestones     $ 13.0    
Payments made upon achievement of development milestone $ 1.0        
Payments made under the supply management agreement       $ 0.0 $ 0.4