Annual report pursuant to Section 13 and 15(d)

Property and Equipment (Details)

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Property and Equipment (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2018
Dec. 31, 2017
Dec. 31, 2016
Property, Equipment and Impairment of Long-Lived Assets      
Property and equipment $ 9,163 $ 7,638  
Less: Accumulated depreciation (5,302) (3,700)  
Total property and equipment, net 3,861 3,938  
Depreciation 1,604 1,527 $ 1,273
Laboratory equipment      
Property, Equipment and Impairment of Long-Lived Assets      
Property and equipment $ 4,926 3,978  
Estimated useful life 5 years    
Assets recorded under capital leases   400  
Assets recorded under capital leases, accumulated depreciation   200  
Computer equipment      
Property, Equipment and Impairment of Long-Lived Assets      
Property and equipment $ 1,080 651  
Estimated useful life 3 years    
Furniture and fixtures      
Property, Equipment and Impairment of Long-Lived Assets      
Property and equipment $ 440 396  
Estimated useful life 4 years    
Leasehold improvements      
Property, Equipment and Impairment of Long-Lived Assets      
Property and equipment $ 2,717 $ 2,613  
Leasehold improvements | Maximum      
Property, Equipment and Impairment of Long-Lived Assets      
Estimated useful life 7 years    
Office Equipment      
Property, Equipment and Impairment of Long-Lived Assets      
Assets recorded under capital leases $ 100    
Assets recorded under capital leases, accumulated depreciation $ 100