Quarterly report pursuant to Section 13 or 15(d)

Stockholders' Equity - Additional Information (Details)

v3.22.1
Stockholders' Equity - Additional Information (Details)
$ / shares in Units, $ in Thousands
 3 Months Ended
Jan. 22, 2021
USD ($)
$ / shares
shares
Dec. 08, 2020
USD ($)
$ / shares
shares
Apr. 09, 2019
USD ($)
Agreement
$ / shares
shares
Mar. 31, 2022
USD ($)
$ / shares
shares
Mar. 31, 2021
USD ($)
shares
Dec. 31, 2021
USD ($)
shares
Dec. 31, 2019
shares
Nov. 30, 2019
shares
Class Of Stock [Line Items]                
Warrants to purchase common stock       2,117,094 2,117,094      
Remeasured fair value of warrants | $       $ 581   $ 3,029    
Change in fair value of warrant liability | $       $ 2,448 $ 7,670      
Number of underwriting agreements | Agreement     2          
Aggregate gross proceeds from public offerings | $     $ 70,000          
Underwriting discounts and commissions and estimated offering expenses payable | $     $ 5,000          
Preferred stock, shares outstanding       0   0    
Warrant issued to purchase common stock       2,117,094 2,117,094      
Series A Preferred Stock                
Class Of Stock [Line Items]                
Share price (in dollars per share) | $ / shares       $ 6.57        
Preferred stock, shares outstanding       0       666
Convertible preferred stock beneficial conversion feature | $       $ 600        
Class A Warrants                
Class Of Stock [Line Items]                
Warrants to purchase common stock             2,118,344  
Warrant exercise price of common stock per share | $ / shares       $ 8.625        
Warrants expiration date       Oct. 10, 2022        
Maximum ownership percentage to total number stock issued and outstanding holder is prohibited from conversion       4.99%        
Notice period for change in owning percentage       61 days        
Warrant issued to purchase common stock             2,118,344  
Fair value of warrants | $       $ 9,000        
Class A Warrants                
Class Of Stock [Line Items]                
Warrants outstanding and remain unexercised excluding Oxford warrants       2,117,094        
Weighted Average | Class A Warrants | Weighted Average Volatility                
Class Of Stock [Line Items]                
Fair value of weighted average volatility       86.06%        
Weighted Average | Class A Warrants | Dividend yield                
Class Of Stock [Line Items]                
Fair value of weighted expected term       3 years 6 months        
Common Stock | Series A Preferred Stock                
Class Of Stock [Line Items]                
Conversion of series A stock into common stock               666,000
Underwritten Public Offering                
Class Of Stock [Line Items]                
Shares issued 5,400,000              
Public offering price per share | $ / shares $ 14.00              
Gross proceeds from common stock | $ $ 75,600              
Underwriting discounts and commissions and other transaction expenses | $ $ 5,100              
Private Placement                
Class Of Stock [Line Items]                
Warrants to purchase common stock       2,828,125 2,828,125      
Gross proceeds of private placement | $   $ 90,500            
Transaction costs | $   400            
Initial fair value of warrants at issuance | $   $ 19,300            
Remeasured fair value of warrants | $       $ 600   $ 3,000    
Warrant issued to purchase common stock       2,828,125 2,828,125      
Private Placement | Common Stock                
Class Of Stock [Line Items]                
Shares issued   10,312,500            
Private Placement | Pre-Funded Warrant                
Class Of Stock [Line Items]                
Warrants to purchase common stock   1,000,000            
Share price (in dollars per share) | $ / shares   $ 8.00            
Warrant issued to purchase common stock   1,000,000            
Private Placement | Warrants                
Class Of Stock [Line Items]                
Share price (in dollars per share) | $ / shares   $ 7.99            
Private Placement | Warrants | Maximum                
Class Of Stock [Line Items]                
Warrants to purchase common stock   2,828,125            
Warrant issued to purchase common stock   2,828,125            
Public Offering | Common Stock Agreement | Class A Warrants                
Class Of Stock [Line Items]                
Warrants to purchase common stock     1,951,844          
Share price (in dollars per share) | $ / shares     $ 7.50 $ 7.50        
Warrant issued to purchase common stock     1,951,844          
Public Offering | Preferred Stock Agreement | Series A Preferred Stock                
Class Of Stock [Line Items]                
Shares issued     666          
Public Offering | Preferred Stock Agreement | Class A Warrants                
Class Of Stock [Line Items]                
Warrants to purchase common stock     166,500          
Share price (in dollars per share) | $ / shares     $ 7,500          
Warrant issued to purchase common stock     166,500          
Public Offering | Common Stock | Common Stock Agreement                
Class Of Stock [Line Items]                
Shares issued     8,667,333