Quarterly report pursuant to Section 13 or 15(d)

Nature of Business - Additional Information (Details)

v3.22.1
Nature of Business - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2019
Organization Consolidation And Presentation Of Financial Statements [Abstract]          
Net Loss $ 25,146 $ 14,228 $ 86,600 $ 84,000 $ 75,400
Accumulated deficit (488,725)   $ (463,579)    
Cash, cash equivalents and marketable securities, fair value $ 112,900