Annual report pursuant to Section 13 and 15(d)

Summary of Significant Accounting Policies - Net Loss per Share (Details)

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Summary of Significant Accounting Policies - Net Loss per Share (Details) - shares
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Anti-dilutive securities                      
Total shares excluded from diluted net loss per share applicable to common stockholders                 2,846,668 2,548,320 15,081,949
Weighted Average Number of Shares Outstanding, Basic and Diluted 26,316,550 26,259,216 25,584,147 23,393,448 23,374,734 22,012,743 2,553,146 2,394,470 25,406,845 12,696,414 1,980,286
Convertible Preferred Stock                      
Anti-dilutive securities                      
Total shares excluded from diluted net loss per share applicable to common stockholders                     12,598,370
Employee Stock options                      
Anti-dilutive securities                      
Total shares excluded from diluted net loss per share applicable to common stockholders                 2,846,668 2,543,435 2,226,698
Restricted stock                      
Anti-dilutive securities                      
Total shares excluded from diluted net loss per share applicable to common stockholders                   4,885 256,881