Annual report pursuant to Section 13 and 15(d)

Commitments and Contingencies - Operating Leases (Details)

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Commitments and Contingencies - Operating Leases (Details)
$ in Thousands
1 Months Ended 12 Months Ended
Mar. 31, 2015
ft²
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Operating leases        
Area of office and laboratory space leased | ft² 21,488      
Term of option to extend the lease   5 years    
Rent expense   $ 900 $ 900 $ 300
Restricted cash, current   193    
Operating leases future minimum payments        
2018   1,288    
2019   1,325    
2020   1,130    
Operating leases future minimum payments   3,743    
Restricted Cash        
Operating leases        
Letter of credit outstanding   $ 500 $ 500