Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS

CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2017	Sep. 30, 2016
Operating activities
Net loss	$ (38,708)	$ (36,778)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	1,137	935
Loss on disposal of assets		3
Stock-based compensation expense	3,148	3,504
Net amortization of premiums and discounts on marketable securities	(27)
Changes in operating assets and liabilities:
Prepaid expenses and other current assets	22	(847)
Accounts receivable	867
Other long-term assets	(370)	(443)
Accounts payable	(295)	1,426
Accrued expenses	849	1,469
Deferred revenue	(550)
Deferred rent and lease incentive	(235)	(209)
Net cash used in operating activities	(34,162)	(30,940)
Investing activities
Purchases of property and equipment	(754)	(2,008)
Purchases of marketable securities	(41,768)
Sales or maturities of marketable securities	27,000
Net cash used in investing activities	(15,522)	(2,008)
Financing activities
Payments on capital lease obligations	(125)	(95)
Proceeds from issuance of common stock through employee benefit plans	918	360
Proceeds from issuance of convertible preferred stock, net of issuance costs		39,813
Proceeds from issuance of common stock through private placement, net of placement agent fees	32,865
Proceeds from initial public offering of common stock, net of issuance costs		50,455
Payments of offering costs	(413)
Net cash provided by financing activities	33,245	90,533
Increase (decrease) in cash and cash equivalents	(16,439)	57,585
Cash and cash equivalents, Beginning of period	58,588	35,909
Cash and cash equivalents, End of period	42,149	93,494
Supplemental disclosure of cash flow information:
Cash paid for interest	8	15
Non-cash investing and financing activities
Conversion of convertible preferred stock into common stock		82,013
Property and equipment received but unpaid as of period end	9	76
Assets acquired under capital lease		$ 17
Offering costs incurred but unpaid as of period end	$ 60