Quarterly report pursuant to Section 13 or 15(d)

Stock-Based Payments - Stock-Based Compensation Expense (Details)

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Stock-Based Payments - Stock-Based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2017
Mar. 31, 2016
Stock-based compensation expense for stock options and restricted common stock granted    
Stock-based compensation expense $ 884 $ 662
Unrecognized compensation cost related to non-vested stock options granted to employees $ 13,000  
Weighted average period over which future compensation cost is expected to be recognized for awards granted to employees 3 years 1 month 6 days  
Unrecognized compensation cost related to non-vested stock options granted to non-employees $ 1,000  
Research and development    
Stock-based compensation expense for stock options and restricted common stock granted    
Stock-based compensation expense 330 560
General and administrative    
Stock-based compensation expense for stock options and restricted common stock granted    
Stock-based compensation expense $ 554 $ 102