Quarterly report pursuant to Section 13 or 15(d)

Nature of Business - Additional Information (Details)

v3.23.1
Nature of Business - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
Sep. 16, 2022
Jul. 03, 2022
Dec. 08, 2020
Mar. 31, 2023
Dec. 31, 2022
Mar. 31, 2022
Class Of Stock [Line Items]            
Accumulated deficit       $ (582,022) $ (558,233)  
Warrants to purchase common stock           211,709
Common stock, shares issued       20,409,130 20,263,116  
Cash, cash equivalents and marketable securities, fair value       $ 165,800    
Private Placement            
Class Of Stock [Line Items]            
Gross proceeds of private placement $ 129,900   $ 90,500      
Transaction costs $ 10,100   $ 400      
Private Placement | Twenty Twenty Two Pre Funded Warrants            
Class Of Stock [Line Items]            
Warrants to purchase common stock 7,426,739          
Share price (in dollars per share) $ 10.34          
Private Placement | 2022 Warrants            
Class Of Stock [Line Items]            
Share price (in dollars per share) $ 10.33          
Private Placement | Common Stock            
Class Of Stock [Line Items]            
Shares issued 6,387,173   1,031,250      
Maximum [Member] | Private Placement | 2022 Warrants            
Class Of Stock [Line Items]            
Warrants to purchase common stock 13,813,912   282,809      
Tyme | Merger Agreement            
Class Of Stock [Line Items]            
Common stock, shares issued   7,500,000        
Acquired net cash, cash equivalents and marketable securities   $ 67,100        
Stock Split Amendment            
Class Of Stock [Line Items]            
Description of reverse stock split the reverse stock split of its common stock, such that every 10 shares of the Company’s common stock held by a stockholder immediately prior to the reverse stock split were combined and reclassified into one share of the Company’s common stock