Schedule of selected quarterly financial information |
|
|
Three Months Ended
|
|
|
|
March 31, 2019
|
|
|
June 30, 2019
|
|
|
September 30, 2019
|
|
|
December 31, 2019
|
|
Revenue
|
|
$
|
454
|
|
|
$
|
462
|
|
|
$
|
558
|
|
|
|
508
|
|
Operating expenses:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Research and development
|
|
|
12,562
|
|
|
|
15,475
|
|
|
|
15,931
|
|
|
|
14,277
|
|
General and administrative
|
|
|
4,865
|
|
|
|
5,195
|
|
|
|
5,016
|
|
|
|
6,402
|
|
Total operating expenses
|
|
|
17,427
|
|
|
|
20,670
|
|
|
|
20,947
|
|
|
|
20,679
|
|
Loss from operations
|
|
|
(16,973
|
)
|
|
|
(20,208
|
)
|
|
|
(20,389
|
)
|
|
|
(20,171
|
)
|
Other income, net
|
|
|
512
|
|
|
|
753
|
|
|
|
596
|
|
|
|
442
|
|
Net loss applicable to common stockholders
|
|
$
|
(16,461
|
)
|
|
$
|
(19,455
|
)
|
|
$
|
(19,793
|
)
|
|
|
(19,729
|
)
|
Net loss per share applicable to common stockholders - basic and diluted
|
|
$
|
(0.49
|
)
|
|
$
|
(0.47
|
)
|
|
$
|
(0.47
|
)
|
|
|
(0.46
|
)
|
Weighted-average number of common shares used in net loss per share applicable to common stockholders - basic and diluted
|
|
|
33,766,333
|
|
|
|
41,673,275
|
|
|
|
42,439,338
|
|
|
|
42,885,208
|
|
|
|
Three Months Ended
|
|
|
|
March 31, 2018
|
|
|
June 30, 2018
|
|
|
September 30, 2018
|
|
|
December 31, 2018
|
|
Revenue
|
|
$
|
370
|
|
|
$
|
375
|
|
|
$
|
412
|
|
|
$
|
893
|
|
Operating expenses:
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Research and development
|
|
|
11,116
|
|
|
|
11,082
|
|
|
|
12,856
|
|
|
|
15,128
|
|
General and administrative
|
|
|
4,075
|
|
|
|
3,841
|
|
|
|
3,876
|
|
|
|
4,372
|
|
Total operating expenses
|
|
|
15,191
|
|
|
|
14,923
|
|
|
|
16,732
|
|
|
|
19,500
|
|
Loss from operations
|
|
|
(14,821
|
)
|
|
|
(14,548
|
)
|
|
|
(16,320
|
)
|
|
|
(18,607
|
)
|
Other income, net
|
|
|
358
|
|
|
|
501
|
|
|
|
583
|
|
|
|
575
|
|
Net loss applicable to common stockholders
|
|
$
|
(14,463
|
)
|
|
$
|
(14,047
|
)
|
|
$
|
(15,737
|
)
|
|
$
|
(18,032
|
)
|
Net loss per share applicable to common stockholders - basic and diluted
|
|
$
|
(0.48
|
)
|
|
$
|
(0.43
|
)
|
|
$
|
(0.47
|
)
|
|
$
|
(0.54
|
)
|
Weighted-average number of common shares used in net loss per share applicable to common stockholders - basic and diluted
|
|
|
30,335,164
|
|
|
|
32,892,712
|
|
|
|
33,653,479
|
|
|
|
33,694,756
|
|
|