Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - License Agreements (Details)

v3.5.0.2
Commitments and Contingencies - License Agreements (Details) - USD ($)
$ in Thousands
 1 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2016
May 31, 2016
Sep. 30, 2015
Apr. 30, 2013
Sep. 30, 2016
Sep. 30, 2015
Dec. 31, 2015
Feb. 28, 2013
Dana Farber                
License Agreements                
Payments due when the Company achieves certain milestones per the license agreement               $ 3,400
Future potential milestone payments due $ 0       $ 0   $ 0  
Whitehead                
License Agreements                
Payments due when the Company achieves certain milestones per the license agreement       $ 3,600        
Future potential milestone payments due 0       0   0  
Service fees paid         $ 800 $ 400 $ 500  
Whitehead | Common Stock                
License Agreements                
Shares issued       171,674        
TMRC                
License Agreements                
Up-front license fee     $ 1,000          
Payment of up-front license fee   $ 500 500          
Payments per indication due upon the successful achievement of clinical and regulatory milestones     $ 13,000     $ 13,000    
Payments made upon achievement of development milestone $ 1,000