Quarterly report pursuant to Section 13 or 15(d)

Commitments and Contingencies - Operating Leases (Details)

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Commitments and Contingencies - Operating Leases (Details)
$ in Thousands
1 Months Ended 3 Months Ended 6 Months Ended
Jan. 08, 2019
ft²
Jan. 01, 2019
USD ($)
Mar. 31, 2015
ft²
Jun. 30, 2019
USD ($)
Jun. 30, 2018
USD ($)
Jun. 30, 2019
USD ($)
Jun. 30, 2018
USD ($)
Operating lease, right-of-use asset       $ 16,831   $ 16,831  
Operating lease liability       17,876   17,876  
Operating lease liability, short term       1,629   1,629  
Operating lease liability, long term       16,247   16,247  
Rent expense       700 $ 200 900 $ 400
Accounting Standards Update 2016-02              
Operating lease, right-of-use asset   $ 1,500   15,800   15,800  
Operating lease liability   2,200          
Operating lease liability, short term   1,100          
Operating lease liability, long term   $ 1,100   $ 15,800   15,800  
Net of tenant allowances           $ 9,300  
Lease operating, discounted borrowing rate       9.30%   9.30%  
Lease practical expedient   true          
Operating Lease March2015              
Area of office and laboratory space leased | ft² | ft²     21,488        
Term of option to extend the lease       5 years   5 years  
Operating Lease, January 2019              
Area of office and laboratory space leased | ft² | ft² 52,859            
Term of option to extend the lease       10 years   10 years  
Letter of credit outstanding       $ 3,100   $ 3,100  
Operating Lease March2015 | Accounting Standards Update 2016-02              
Operating lease liability, short term       1,200   1,200  
Operating lease liability, long term       400   400  
Operating Lease, January 2019 | Accounting Standards Update 2016-02              
Operating lease liability, short term       400   400  
Operating lease liability, long term       $ 15,800   $ 15,800