Quarterly report pursuant to Section 13 or 15(d)

Stock-Based Payments - Stock-Based Compensation Expense (Details)

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Stock-Based Payments - Stock-Based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Stock-based compensation expense for stock options and restricted common stock granted        
Stock-based compensation expense $ 1,148 $ 613 $ 1,810 $ 1,124
Unrecognized compensation cost related to non-vested stock options and unvested restricted common stock 8,100   $ 8,100  
Weighted average period over which future compensation cost is expected to be recognized     2 years 10 months 24 days  
Research and development        
Stock-based compensation expense for stock options and restricted common stock granted        
Stock-based compensation expense 929 535 $ 1,489 997
General and administrative        
Stock-based compensation expense for stock options and restricted common stock granted        
Stock-based compensation expense $ 219 $ 78 $ 321 $ 127