Audit Committee Position

Marsha H. Fanucci

Former Chief Financial Officer, Millennium Pharmaceuticals

Marsha H. Fanucci is has served in a number of executive leadership positions at Millennium Pharmaceuticals from 2000 to 2009, including Chief Financial Officer and Senior Vice President of Strategy, Vice President of Finance and Strategy, and Vice President of Corporate Development and Strategy. During her tenure, Ms. Fanucci directly contributed to a series of strategic processes, advanced Millennium to profitability and was instrumental in the acquisition by Takeda Pharmaceutical Company in 2008 for $8.8 billion. Previously, Ms. Fanucci was Vice President of Corporate Development and Strategy at Genzyme Corp. and Vice President and Director at Arthur D. Little. Ms. Fanucci serves on the boards of directors of several biotech companies, including Alnylam Pharmaceuticals, FORMA Therapeutics, Ironwood Pharmaceuticals and Momenta Pharmaceuticals, and non- profit organization The Schwartz Center for Compassionate Care. Ms. Fanucci received a B.S. in pharmacy from West Virginia University Medical School and an M.B.A. from Northeastern University.

Chair

Mark Alles

Former Chairman and CEO, Celgene Corp.

Mr. Alles is a recognized biopharmaceutical expective with a proven record of building successful globally oncology organizations and commercializing innovative therapies over his 30-year career. He is the former Chairman and Chief Executive Officer of Celgene Corporation, now a subsidiary of Bristol-Myers Squibb Company (BMS). In his 16-year tenure at Celgene, Mr. Alles led the expansion of the company from a US-based organization with less than 500 employees into a global enterprise serving patients in more than 50 countries with 8,800 employees. He held a series of commercial and leadership roles of escalating responsibility, consistently delivering industry-leading financial performance. He led teams that completed several multibillion-dollar company or asset acquisitions, built a diverse suit of globally marketed medicines and a pipeline of high potential therapeutics for cancer and serious inflammatory disease, all of which ultimately led to the $74 billion acquisition of Celgene by BMS.

Before joining Celgene, Mr. Alles was Vice President of the U.S. Oncology business unit at Aventis Pharmaceuticals and served in other senior commercial management roles at Aventis (Rhône-Poulenc Rorer). He began his career in the pharmaceutical industry at Bayer and worked at Centocor before its acquisition by Johnson & Johnsonn. He is currently Chairman of Turning Point Therapeutics, Inc., a public oncology company, and also serves on the boards of Antengene Corporation Limited and BioMarin Pharmaceuticals., all public biopharmaceutical companies. He is a member of the board and Consulting CEO for PIKSci, Inc., a private biotechnology company. Mr. Alles received a bachelor’s degree from Lock Haven University of Pennsylvania and served as a Captain in the United States Marine Corps.

Member

Andrew Oh, M.B.A

Senior Partner, Flagship Pioneering and Former Chief Financial Officer, Rubius Therapeutics

Andrew Oh is a Senior Partner at Flagship Pioneering. He most recently served as Chief Financial Officer of Rubius Therapeutics. Before that, Mr. Oh was a pharmaceutical analyst and portfolio manager at leading financial institutions, including Leerink Pharmaceutical Investments, where he was the Co-Founder, Chief Investment Officer and Chief Operating Officer, and Fidelity Investments. Earlier, Mr. Oh worked as a sell-side analyst, covering global pharmaceutical companies at Leerink, J.P. Morgan and Stifel Financial. He holds an M.B.A. from Northwestern’s Kellogg Graduate School of Management and a B.A. in Biology from Washington University in St. Louis.

Member

Audit Committee Charter

Download
Compensation Committee Position

Peter Wirth

Chairman of the Board
Former EVP, Legal and Corporate Development, Genzyme

Peter Wirth is an industry veteran with a track record of value creation in biotechnology. Mr. Wirth was a senior executive at Genzyme from 1996 until its acquisition by Sanofi in 2011, most recently serving as Executive Vice President, Legal and Corporate Development, Chief Risk Officer and Corporate Secretary. During his time at Genzyme, Mr. Wirth had senior management responsibility for the company’s legal function, corporate development function, molecular oncology division, polymer drug discovery and development division and enterprise risk management function. He was instrumental in helping build Genzyme from a small start-up to a diversified, multi-billion dollar enterprise with more than 12,000 employees in locations spanning the globe. Prior to Genzyme, Mr. Wirth practiced law at Palmer & Dodge LLP, where he was head of the firm’s biotechnology practice group and served as outside counsel for Genzyme as well as numerous other biopharmaceutical companies. He is currently Chairman of FORMA Therapeutics, a small molecule drug discovery company, Executive Chairman of ZappRx, a digital health company, and Senior Advisor to Zai Lab Limited, a Shanghai-based biopharmaceutical company. Mr. Wirth was a 2012 Advanced Leadership Fellow at Harvard University. He received his B.A. from the University of Wisconsin-Madison and his J.D. from Harvard Law School.

Chair

Deborah Dunsire, M.D.

President and Chief Executive Officer of H. Lundbeck A/S

Dr. Dunsire currently serves as President and Chief Executive Officer of H. Lundbeck A/S, a global pharmaceutical company focused exclusively on treatments for brain disease. She has held the position since September 2018. She previously served as President and Chief Executive Officer and a Director of Xtuit Pharmaceuticals, Inc., a private biopharmaceutical company, from January 2017 to March 2018. Prior to her position at Xtuit, she served as President and Chief Executive Officer and a Director of FORUM Pharmaceuticals Inc., a private pharmaceutical company, from July 2013 to May 2016. Prior to FORUM, Dr. Dunsire worked for Takeda Pharmaceutical Company Limited as a corporate officer from June 2010 to June 2011 and a Director from June 2011 to June 2013. She served as President, Chief Executive Officer and a Director of Millennium Pharmaceuticals, Inc. between 2005 and 2008, when it was acquired by Takeda, and then as President and Chief Executive Officer of Millennium: The Takeda Oncology Company after the acquisition between 2008 and 2013. Prior to Millennium, Dr. Dunsire held various roles of increasing responsibility at Novartis Pharma AG between 1988 and 2005. She currently serves as a Board member of Ultragenyx Pharmaceutical Inc. and previously served on the boards of Alexion Pharmaceuticals and Allergan. Dr. Dunsire obtained an MBBCh from the University of the Witwatersrand in South Africa.

Member

Timothy Tyson, M.B.A, M.P.A.

Chairman and Chief Executive Officer of TriRx Pharmaceutical Services, LLC

Timothy C. Tyson is a former member of the TYME Board of Directors and an experienced pharmaceutical executive. He is currently Chairman and Chief Executive Officer of TriRx Pharmaceutical Services, LLC and Chairman of Thayer Leadership. Mr. Tyson previously held executive level positions at various pharmaceutical companies, including serving as Chairman of Icagen Inc., Chairman and Chief Executive Officer of Avara Pharmaceutical Services, Inc., Chairman and Chief Executive Officer of Aptuit LLC and Chief Executive Officer, Chief Operating Officer and President of Valeant Pharmaceuticals International. Prior to that, Mr. Tyson was President at GlaxoSmithKline where he worked for 15 years. He holds an M.B.A. and an M.P.A, both from Jacksonville State University, and an undergraduate degree in Engineering from the United States Military Academy at West Point.

Member

Compensation Committee Charter

Download
Nominating and Corporate Governance Committee Position

Richard A. Young, Ph.D.

Richard A. Young, Ph.D., is a member of the Whitehead Institute and professor of Biology at the Massachusetts Institute of Technology. In May 2012, he was elected into the National Academy of Sciences. Dr. Young’s research focuses on the regulatory circuitry that controls the gene expressions programs in each cell, including mapping the regulatory circuitry that controls cell state and differentiation in mice and humans. Experimental and computational technologies are used to determine how signaling pathways, transcription factors, chromatin regulators and small RNAs control gene expression programs in embryonic stem cells. Dr. Young has served as an advisor to Science magazine and the World Health Organization. In 2006, Dr. Young was recognized as one of the top 50 leaders in science, technology and business by Scientific American. His awards include a Burroughs Wellcome Scholarships, the Chiron Corporation Biotechnology Research Awards, and Yale’s Wilbur Cross Medal. Dr. Young received his Ph.D. from Yale University.

Chair

Srinivas Akkaraju, M.D., Ph.D.

Founder and Managing General Partner at Samsara BioCapital

Srinivas Akkaraju, M.D., Ph.D., has nearly 20 years of investment and operational experience in the life sciences sector. Dr. Akkaraju is a Founder and Managing General Partner at Samsara BioCapital. Prior to founding Samsara BioCapital, he served as a General Partner of Sofinnova Ventures from April 2013 to June 2016, Managing Director of New Leaf Venture Partners from January 2009 to April 2013, and Managing Director of Panorama Capital, a private equity firm that he helped found, from September 2006 to December 2008. Before co-founding Panorama Capital, he was a Partner at J.P. Morgan Partners, and earlier in his career, he was in Business and Corporate Development at Genentech (now a wholly owned member of The Roche Group). Dr. Akkaraju currently serves as chairman of the board of Versartis and as a director of Intercept Pharmaceuticals, Seattle Genetics and aTyr Pharma. Previously, he served on the boards of Barrier Therapeutics, Eyetech Pharmaceuticals, ZS Pharma, Synageva Biopharma Corp. and Amarin Corp. Dr. Akkaraju received an M.D. and a Ph.D. in Immunology from Stanford University and undergraduate degrees in Biochemistry and Computer Science from Rice University.

Member

S. Gail Eckhardt, M.D.

Chair of the Department of Oncology, University of Texas at Austin’s Dell Medical School

Dr. Eckhardt is a highly respected oncologist and a leader in targeted oncology drug development. She is a tenured Professor, inaugural Director of the Livestrong Cancer Institutes, Chair of the Department of Oncology, and Associate Dean of Cancer Programs at the University of Texas at Austin’s Dell Medical School. Prior to joining UT Austin, Dr. Eckhardt was at the University of Colorado School of Medicine, where she was Division Head of Medical Oncology, Associate Director for Translational Research at the University of Colorado Comprehensive Cancer Center and Director of the Phase I Program and Fellowship. Dr. Eckhardt has served on numerous committees and study sections, including the ASCO Molecular Oncology Task Force, the ASCO Board of Directors, the FDA Oncology Drugs Advisory Committee, and the National Cancer Institute (NCI) Cancer Centers Study Section. She is a member of the NCI Investigational Drug Steering Committee and serves on 10 external advisory boards of NCI-designated cancer centers, was a lead mentor in ASCO’s Leadership Development Program and currently is a member of the Board of Directors of the Association of American Cancer Institutes (AACI).

Dr. Eckhardt is the Principal Investigator on grants involving early clinical trials and colorectal cancer research, has conducted numerous phase I and II clinical trials and has published over 200 manuscripts. Her area of interest is in the preclinical and early clinical development of combinations of molecularly targeted compounds, with a laboratory focus on colorectal cancer. Dr. Eckhardt earned her undergraduate degree in chemistry from Stephen F. Austin State University and her medical degree from the University of Texas Medical Branch in Galveston. She conducted her internship and residency in Internal Medicine at the University of Virginia Medical School, followed by a post-doctoral research fellowship in Experimental and Molecular Medicine at Scripps Research Institute in La Jolla, California, and a fellowship in Medical Oncology at the University of California San Diego.

Member

Nominating and Corporate Governance Committee Charter

Download
R&D Committee Position

S. Gail Eckhardt, M.D.

Chair of the Department of Oncology, University of Texas at Austin’s Dell Medical School

Dr. Eckhardt is a highly respected oncologist and a leader in targeted oncology drug development. She is a tenured Professor, inaugural Director of the Livestrong Cancer Institutes, Chair of the Department of Oncology, and Associate Dean of Cancer Programs at the University of Texas at Austin’s Dell Medical School. Prior to joining UT Austin, Dr. Eckhardt was at the University of Colorado School of Medicine, where she was Division Head of Medical Oncology, Associate Director for Translational Research at the University of Colorado Comprehensive Cancer Center and Director of the Phase I Program and Fellowship. Dr. Eckhardt has served on numerous committees and study sections, including the ASCO Molecular Oncology Task Force, the ASCO Board of Directors, the FDA Oncology Drugs Advisory Committee, and the National Cancer Institute (NCI) Cancer Centers Study Section. She is a member of the NCI Investigational Drug Steering Committee and serves on 10 external advisory boards of NCI-designated cancer centers, was a lead mentor in ASCO’s Leadership Development Program and currently is a member of the Board of Directors of the Association of American Cancer Institutes (AACI).

Dr. Eckhardt is the Principal Investigator on grants involving early clinical trials and colorectal cancer research, has conducted numerous phase I and II clinical trials and has published over 200 manuscripts. Her area of interest is in the preclinical and early clinical development of combinations of molecularly targeted compounds, with a laboratory focus on colorectal cancer. Dr. Eckhardt earned her undergraduate degree in chemistry from Stephen F. Austin State University and her medical degree from the University of Texas Medical Branch in Galveston. She conducted her internship and residency in Internal Medicine at the University of Virginia Medical School, followed by a post-doctoral research fellowship in Experimental and Molecular Medicine at Scripps Research Institute in La Jolla, California, and a fellowship in Medical Oncology at the University of California San Diego.

Chair

Srinivas Akkaraju, M.D., Ph.D.

Founder and Managing General Partner at Samsara BioCapital

Srinivas Akkaraju, M.D., Ph.D., has nearly 20 years of investment and operational experience in the life sciences sector. Dr. Akkaraju is a Founder and Managing General Partner at Samsara BioCapital. Prior to founding Samsara BioCapital, he served as a General Partner of Sofinnova Ventures from April 2013 to June 2016, Managing Director of New Leaf Venture Partners from January 2009 to April 2013, and Managing Director of Panorama Capital, a private equity firm that he helped found, from September 2006 to December 2008. Before co-founding Panorama Capital, he was a Partner at J.P. Morgan Partners, and earlier in his career, he was in Business and Corporate Development at Genentech (now a wholly owned member of The Roche Group). Dr. Akkaraju currently serves as chairman of the board of Versartis and as a director of Intercept Pharmaceuticals, Seattle Genetics and aTyr Pharma. Previously, he served on the boards of Barrier Therapeutics, Eyetech Pharmaceuticals, ZS Pharma, Synageva Biopharma Corp. and Amarin Corp. Dr. Akkaraju received an M.D. and a Ph.D. in Immunology from Stanford University and undergraduate degrees in Biochemistry and Computer Science from Rice University.

Member

Deborah Dunsire, M.D.

President and Chief Executive Officer of H. Lundbeck A/S

Dr. Dunsire currently serves as President and Chief Executive Officer of H. Lundbeck A/S, a global pharmaceutical company focused exclusively on treatments for brain disease. She has held the position since September 2018. She previously served as President and Chief Executive Officer and a Director of Xtuit Pharmaceuticals, Inc., a private biopharmaceutical company, from January 2017 to March 2018. Prior to her position at Xtuit, she served as President and Chief Executive Officer and a Director of FORUM Pharmaceuticals Inc., a private pharmaceutical company, from July 2013 to May 2016. Prior to FORUM, Dr. Dunsire worked for Takeda Pharmaceutical Company Limited as a corporate officer from June 2010 to June 2011 and a Director from June 2011 to June 2013. She served as President, Chief Executive Officer and a Director of Millennium Pharmaceuticals, Inc. between 2005 and 2008, when it was acquired by Takeda, and then as President and Chief Executive Officer of Millennium: The Takeda Oncology Company after the acquisition between 2008 and 2013. Prior to Millennium, Dr. Dunsire held various roles of increasing responsibility at Novartis Pharma AG between 1988 and 2005. She currently serves as a Board member of Ultragenyx Pharmaceutical Inc. and previously served on the boards of Alexion Pharmaceuticals and Allergan. Dr. Dunsire obtained an MBBCh from the University of the Witwatersrand in South Africa.

Member

Richard A. Young, Ph.D.

Member, Whitehead Institute

Richard A. Young, Ph.D., is a member of the Whitehead Institute and professor of Biology at the Massachusetts Institute of Technology. In May 2012, he was elected into the National Academy of Sciences. Dr. Young’s research focuses on the regulatory circuitry that controls the gene expressions programs in each cell, including mapping the regulatory circuitry that controls cell state and differentiation in mice and humans. Experimental and computational technologies are used to determine how signaling pathways, transcription factors, chromatin regulators and small RNAs control gene expression programs in embryonic stem cells. Dr. Young has served as an advisor to Science magazine and the World Health Organization. In 2006, Dr. Young was recognized as one of the top 50 leaders in science, technology and business by Scientific American. His awards include a Burroughs Wellcome Scholarships, the Chiron Corporation Biotechnology Research Awards, and Yale’s Wilbur Cross Medal. Dr. Young received his Ph.D. from Yale University.

Member

R&D Committee Charter

Download