Exhibit 107

Calculation of Filing Fee Tables

Form S-8

(Form Type)

Syros Pharmaceuticals, Inc.

(Exact Name of Registrant as Specified in its Charter)

Table 1—Newly Registered Securities

 

 

Security Type   Security
Class Title		   Fee
Calculation
Rule		   Amount
Registered
(1)		   Proposed
Maximum
Offering
Price Per
Unit		   Maximum
Aggregate
Offering Price		   Fee Rate   Amount of
Registration
Fee
               
Equity   Common Stock, $0.001 par value per share   Other   32,035 (2)   $6.28 (3)   $201,179.80 (3)  

$147.60

per

$1,000,000

   $29.70
         
Total Offering Amounts     $201,179.80     $29.70
         
Total Fee Offsets         $—
         
Net Fee Due               $29.70

 

(1)

In accordance with Rule 416 under the Securities Act of 1933, as amended (the “Securities Act”), this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued to prevent dilution resulting from stock splits, stock dividends or similar transactions.

(2)

Consists of 32,035 shares issuable under the 2016 Employee Stock Purchase Plan pursuant to such plan’s evergreen provision.

(3)

Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act, and based upon the average of the high and low prices of the registrant’s common stock as reported on the Nasdaq Global Select Market on March 21, 2024.